The cartridges remain sterlised for 3 years from the manufacture date. The manufacture date, the expiry date and the lot numbers are all printed on each individual blister pack and also on the box as well.

No, RMS cartridges are specifically designed to be used with RM Star.

Yes, the cartridges are sterlised and packaged in temper/contamination proof blister packs.

• Cartridge Length: 4 cm
• Cartridge Diameter: 1 cm (the treating surface) ~ 2 cm (body)
• Number of Needles per Cartridge: 13
• Needle Thickness:
• Needle length: adjustable between 0 ~ 2 mm
• Needle material: 24K Gold Plated Surgical Grade Stainless Steel

1. Fractionated microneedle radiofrequency for the treatment of periorbital wrinkles
   This clinical study suggests that FMRF is a safe and tolerable method for successful treatment of periorbital wrinkles.
   Published in The Journal of Dermatology by Kim et al in 2012
2. Skin Rejuvenation by microneedle fractional radiofrequency treatment in Asian skin: clinical and histological analysis
   Microneedle fractional RF is a safe and effective skin rejuvenation method in Asians.
   Published in Lasers in Surgery and Medicine by Seo et al in 2012
3. Comparison of microneedle fractional radiofrequency therapy with intradermal botulinum toxin A injection for periorbital rejuvenation
   BoNT/A injection rapidly improved periorbital wrinkles, but the effect decreased up to week 18. Compared to BoNT/A injection, MFR therapy showed gradual and long-term improvement in periorbital rejuvenation.
   Published in Dermatology by Jeon et al in 2013
4. Prospective multicenter clinical trial of a minimally invasive temperature-controlled bipolar fractional radiofrequency system for rhytid and laxity treatment
   Real-time temperature-controlled FRF is a highly reproducible, safe, effective nonsurgical treatment of face and neck rhytides and laxity and provides important insights into neocollagenesis, neoelastogenesis, and clinical outcomes.
   Published in Dermatologic Surgery by Alexiades et al in 2013
5. Clinical Study of Facial Wrinkle Treatment with Fractional Microneedle Radio Frequency System
   Fractional microneedle RF system was effective and safe in the treatment of facial wrinkles.
   Published in Medical Lasers by Park et al in 2014
6. Evaluation of Microneedling Fractional Radiofrequency Device for Treatment of Acne Scars
   Microneedling fractional radiofrequency is efficacious for the treatment of moderate and severe acne scars.
   Published in Journal of Cutaneous and Aesthetic Surgery by Chandrashekar et al in 2014
7. Treatment of periorbital wrinkles with a novel fractional radiofrequency microneedle system in dark-skinned patients
   The system may be an effective and safe treatment option for periorbital wrinkles in dark-skinned Korean patients.
   Published in Dermatologic Surgery by Lee et al in 2015
8. Randomized, blinded, 3-arm clinical trial assessing optimal temperature and duration for treatment with minimally invasive fractional radiofrequency
   The optimal target dermal temperature for facial and neck rhytide and laxity treatment is 67°C and duration of 3 to 4 seconds with a 100% response rate after a single FRF treatment.
   Published in Dermatologic Surgery by Alexiades et al in 2015
9. Non-insulated smooth motion, micro-needles RF fractional greatment for winkle reduction and lifting of the lower face: international study
   This multicenter study showed significant wrinkle reduction, skin tightening, and lifting of the mid and lower face with the noninsulated fractional RF microneedling system.
   Published in Lasers in Surgery and Medical by Gold et al in 2016
10. Curative effects of microneedle fractional radiofrequency system on skin laxity in Asian patients: a prospective, double-blind, randomized, controlled face-split study
    MFRS is an effective method to improve skin laxity. Thermal lesion approach seems to provide better outcomes when applied to deep dermal layers. It is necessary to consider the skin thickness of different facial regions when choosing the treatment depth.
    Published in Journal of Cosmetic Laser Therapy by Lu et al in 2016
11. A prospective study of the safety and efficacy of a microneedle fractional radiofrequency system for global facial photoagiaging in Chinese patients
    This MFRS is effective for facial skin rejuvenation in Chinese patients. The therapy also seems safe and well tolerated.
    Published in Dermatologic Surgery by Zhang et al in 2018
12. Microneedle fractional radiofrequency treatment of facial photoageing as assessed in a split-face model
    MFR appears to be an excellent treatment for photodamaged facial skin in Chinese patients.
    Published in Clinical and Experimental Dermatology by Liu et al in 2019
13. Multimodal Radiofrequency Application for Lower Face and Neck Laxity
    While this combination RF treatment (FaceTite bipolar RF and fractional bipolar RF) does not aim to replace a facelift/necklift in appropriate candidates, it does broaden the plastic surgeons' armamentarium to potentially fill a treatment gap.
    Published in PRS Global Open by Dayan et al in 2020
14. The Efficacy and safety of microneedle monopolar radiofrequency for the treatment of periorbital wrinkles
    We demonstrated the efficacy and safety of the microneedle monopolar RF device in treating periorbital wrinkles. The LMN was superior to the SMN in reducing VISIA wrinkle score.
    Published in Journal of Dermatological Treatment by Kwon et al in 2021
15. Radiofrequency microneedling: a comprehensive and critical review
    Radiofrequency microneedling is an effective intervention that can be used repeatedly and safely in combination with other treatment modalities and in individuals with darker skin phototypes. Radiofrequency microneedling-induced dermal remodeling and neocollagenesis are slow and progressive but continue to improve even 6 months after treatment.
    Published in Dermatologic Surgery by Tan et al in 2021
16. Transcutaneous Radiofrequency Microneedling in the Facial Plastic Surgeon's Practice: A Review
    RF microneedling addresses aesthetical and dermatological concerns for a diverse variety of patients in whom surgical intervention may not be desired. Morpheus8 has unique technological properties and advances that make it the preferred device for many practices.
    Published in Facial Plastic Surgery & Aesthetic Medicine by Magro et al in 2022
17. Clinical and histological evaluation of microneedle fractional radiofrequency treatment on facial fine lines and skin laxity in Koreans
    Temperature-controlled bipolar MFR is a minimally invasive treatment option to consider for facial fine lines and laxity via neo-collagenesis and neo- elastogenesis. The procedure was safe and clinically effective.
    Published in Journal of Cosmetic Dermatology by Suh et al in 2022
18. Can Microneedle Fractional Radiofrequency System Treatment Impair the Skin Barrier Function in Chinese Patients? A Prospective Clinical Trial
    MFRS is a safe and effective treatment for facial cosmetic conditions. The skin barrier function is not impaired by MFRS treatment, since it does not cause skin sensitivity or melasma exacerbation.
    Published in Dermatologic Therapy by Wu et al in 2022
19. Fractional microneedle radiofrequency - mechanism of action and assessment of safety, effectiveness in the treatment, and possible side effects based on a review of scientific literature
    FMR has a wide range of positive effects such as skin rejuvenation, skin tightening, facial and body scar remodeling, and hair growth through transdermal collagen induction.
    Published in Journal of Education Health and Sport by Nowak et al in 2023
20. Efficacy Assessment of a Pulsed-Type Bipolar Radiofrequency Microneedling Device for Treating Facial Acne Vulgaris Using a Skin-Color Imaging System; A Pilot Study
    Thus, such pulsed-type bipolar radiofrequency microneedling is a safe and effective treatment for acne and post-inflammatory erythema.
    Published in Journal of Costmetic Dermatology by Huang et al in 2023
21. Radiofrequency Microneedling: Technology, Devices, and Indications in the Modern Plastic Surgery Practice
    The authors find herein that radiofrequency microneedling is a safe adjunctive tool to surgical aesthetic procedures. The addition of radiofrequency poses an advance over traditional microneedling devices for skin tightening, with improvements in both safety and efficacy over time.
    Published in Aesthetic Surgery Journal Open Forum by Shauly et al in 2023
22. Targeting the dermis for melasma maintenance treatment
    The continuous microneedling RF therapy is beneficial in maintaining the conventional therapy of melasma suggesting the protective effect of dermal targeting therapy in melasma development.
    Published in Scientific Reports by Han et al in 2024